dUTP相关论文
目的探索骨髓增生异常综合征(MDS)造血细胞中表皮生长因子受体(EGFR)表达及其与细胞凋亡的关系.方法取18例MDS患者骨髓有核细胞经......
N-methyl-D-aspartate receptor subtype 3A promotes apoptosis in developing mouse brain exposed to hyp
In the present study, 7 day postnatal C57/BL6 wild-type mice (hyperoxia group) and 7 day postnatal N-methyl-D-aspartate ......
目的:研究早期糖尿病视网膜病变大鼠视网膜毛细血管细胞凋亡及其特征。方法:腹腔内注射链脲佐菌素诱导糖尿病大鼠模型。应用过碘酸......
为了加快基因功能的研究 ,利用已有的来源于不同组织的cDNA克隆 ,并通过交换和购买补充了低丰度和染色体覆盖不完全的部分cDNA ,研......
A diabetes mellitus model was established through single intraperitoneal injection of streptozotocin into rats. Seven da......
Naofen promotes TNF-α-mediated apoptosis of hepatocytes by activating caspase-3 in lipopolysaccharid
AIM:To investigate whether naofen is involved in tumor necrosis factor(TNF)-α-mediated apoptosis of hepatocytes induced......
Background:Bone marrow mesenchymal stem cell (MSC) transplantation is a promising strategy in the treatment of myocardia......
Objective:The aim of this study was to test the protective effect of mesenchymal stem cells(MSCs) on cardiomyocytes in v......
Activation of calcium-sensing receptors is associated with apoptosis in a model of simulated cardiom
Objective:Calcium-sensing receptors(CaSRs)are G-protein coupled receptors which maintain systemic calcium homeostasis an......
Brain natriuretic peptide inhibits myocardial apoptosis caused by ischemia-reperfusion injury in rat
Background This study aimed to investigate the effects of brain natriuretic peptide(BNP) on myocardial ischemiareperfusi......
The cardioprotection induced by lipopolysaccharide involves phosphoinositide 3-kinase/Akt and high m
Objective:The mechanisms by which lipopolysaccharide(LPS)pretreatment induces cardioprotection following ischaemia/reper......
Fas/APO-1是一种细胞表面蛋白,也是肿瘤坏死因子受体,其与Fas配体结合可导致细胞凋亡。对10例中耳手术中取得的胆脂瘤和耳后皮肤进......
目的 :利用内皮细胞抑制素进行肿瘤抗血管基因治疗的尝试。方法 :用RT PCR从鼠肝脏扩增出内皮细胞抑制素cDNA ,经测序证实后 ,装入......
Objective.To determine the apoptotic and proliferative activities in various ovarian epithelial tumors.Methods.Formalin-......
AIM:To identify new diagnostic markers and drug targets,the gene expression profiles of pancreatic cancer werecompared ......
AIM:To study the effect of TNP-470 on cell growth,proliferation and apoptosis in human colon cancer xenograftsin nude m......
Background We investigated the expression and role of T N4 in the oncogenesis of human hepatocellular carcinoma (HCC) fr......
Gene expression profile of the lung adenosquamous carcinoma was characterized by using cDNA microarray chip containing 4......
AIM: To find out key genes responsible for hepatocarcinogenesis and to further understand the underlying molecular mecha......
AIM: To study the effect of sulindac on colon cancer induction in mice. METHODS: The chemo-preventive action of 80 ppm s......
凋亡相关基因如 ICE(IL-1βconverting enzyme),Fas/Apo-1,Fas-L等与细胞毒T细胞(cytotoxic T cell,CTL)效应以及免疫应答的调节包......
为探讨不同浓度亚砷酸钠对诱导 NB_4细胞凋亡能力的影响,采用流式细胞术、DNA 电泳和免疫印迹进行研究。结果发现:①经0.8~8 μmol......
目的 探讨鼻咽癌 (NPC)组织bcl 2及EB病毒潜伏膜蛋白 (LMP)表达与放射诱发细胞凋亡的关系。方法 采用免疫组化S P法及TdT酶介导......
AIM:To investigate the action of apoptosis in occurrence ofliver cacinomas in vivo and the biological effect of Solanum......
Neuronal apoptosis and neurofilament protein expression in the lateral geniculate body of cats follo
BACKGROUND: The visual pathway have 6 parts, involving optic nerve, optic chiasm, optic tract, lateral geniculate body, ......
Hypertonic saline resuscitation reduces apoptosis of intestinal mucosa in a rat model of hemorrhagic
Objective: To investigate the early effects of hypertonic and isotonic saline solutions on apoptosis of intestinal mucos......
目的探讨细胞凋亡及Bcl-2蛋白表达与神经母细胞瘤(NB)发生发展和预后的关系。方法应用SAB免疫组化及TUNEL技术对17例NB中Bcl-2蛋白......
作者将聚合酶链反应(PCR)用于检测高免疫人群中可疑百日咳病人样本,并与培养、血清学试验和临床症状作了比较,评价PCR的敏感性与......
目的 观察幽门螺杆菌 (HP)阳性的胃溃疡病人在溃疡愈合前后胃上皮细胞凋亡及HP检测的情况。方法 采用检测DNA裂解的末端脱氧核苷......
目的 利用原代培养肝细胞 ,研究鹅脱氧胆酸损害肝细胞机制。方法 SD大鼠肝细胞原代短期培养 ,分别加入不同浓度的甘氨鹅脱氧胆酸......
Effect of caffeic acid phenethyl ester on proliferation and apoptosis of hepatic stellate cells in v
AIM:To investigate the role of nuclear factor-kB (NF-kB)inhibitor caffeic acid phenethyl ester (CAPE) in theproliferati......
BACKGROUND: At present, there is still lack of effective drugs for chronic spinal cord injury, whereas it is found recen......
Expression of NF-κB in Schwann cells and its effect on motor neuron apoptosis in spinal cord followi
Objective: To explore the expression of nuclear factor-kappa B (NF-κB) in Schwann cells (SCs) and its effect on motor n......
BACKGROUND: The high concentration of glutamate release is the main cause for neuronal cell death. The relationship betw......
Multiple gene differential expression patterns in human ischemic liver:Safe limit of warm ischemic t
AIM:To investigate the multiple gene differential expressionpatterns in human ischemic liver and to produce the evidenc......
Intravenous acid fibroblast growth factor protects intestinal mucosal cells against ischemia-reperfu
AIM: To detect the effect of acid fibroblast growth factor (aFGF) on apoptosis and gene expression of bax and bcl-2 gene......
Bile salts inhibit growth and induce apoptosis of culture human normal esophageal mucosal epithelial
AIM: To investigate the effect of six bile salts: glycocholate (GC), glycochenodeoxycholate (GCDC), glycodeoxycholate (G......
Acid fibroblast growth factor reduces rat intestinal mucosal damage caused by ischemia-reperfusion i
AIM: To detect the effects of acid fibroblast growth factor (aFGF) on apoptosis and proliferation of intestinal epitheli......
Neuroprotective effects of subthalamic nucleus high-frequency stimulation on substantia nigra neuron
BACKGROUND:Deep-brain stimulation has proven to be beneficial in the treatment of Parkinson’s disease(PD) patients.OBJE......
BACKGROUND:Basal cell lymphoma-extra large (bcl-xl) can inhibit neuronal apoptosis by stabilizing the mitochondrial memb......
Objective: To investigate the effects and underlying mechanisms of different doses of nerve growth factor(NGF) pretreatm......
AIM: To find the relationship between hepatitis B virus (HBV) and hepatocytes during the initial state of infection by c......